Low Price Freeze Dryer Machine for Pharmaceutical API Herbal Medicine Chinese Medicine Extracts Biomedical Vaccines Antibiotic Hormone Enzyme Serum Lyophilizer

1. Working Principle of Vacuum Freeze Dryer:
Freeze Dryer, also known as Lyophilizer, is widely used for pharmaceutical and biological industries.
Freeze drying technology, also known as lyophilisation or cryodesiccation, is a low temperature dehydration process that involves freezing the product, lowering pressure, then removing the ice by sublimation. This is in contrast to dehydration by most conventional methods that evaporate water using heat.
A freeze-dryer consists of  a vacuum chamber, shelves, process condenser, shelf-fluid system, refrigeration system, vacuum system, and control system.
There are four stages in the complete freeze drying process: pretreatment, freezing, primary drying, and secondary drying. Usually, the freezing temperatures are between −50 °C (−58 °F) and −80 °C (−112 °F).
 




2. Application of Lyophilizer in Pharmaceuticals and Biotechnology:
Common use of pharmaceutical freeze dryer is to produce lyophilized vials, that is using freeze-drying process to increase the shelf life of the products, such as live virus vaccines, biologics and other injectables(injection powders), by removing the water from the material and sealing the material in a glass vial, the material can be easily stored, shipped, and later reconstituted to its original form for injection and for self-administration by a patient.
Freeze-dried biological products and bio-pharmaceuticals include many kinds of vaccines, antihemophilic factor VIII, anti-blood clot medicine, and wasp venom allergenic extract. Many bio-pharmaceutical products based on therapeutic proteins such as monoclonal antibodies require lyophilization for stability.
Freeze-dryers are also used in manufacturing of raw materials for pharmaceutical use. Active Pharmaceutical Ingredients (APIs) are lyophilized to achieve chemical stability under room temperature storage. Bulk lyophilization of APIs is typically conducted using trays instead of glass vials.
And the freeze dryer is also widely used in Chimical, food, health product industry and so on. The freeze dried food produced by Lyophilizer features long period of quality assurance, good re-hydration nature, good-looking color, good flavor, taste and high content of nutritious components the dried food basically remains unchanged in its volume and shape, looks like sponge and has no shrinking.

Pharmaceutical industry:
Vacuum freeze-drying can be used in the drying of Chinese and western leechdom such as blood serum, blood plasma, bacteria, enzyme, antibiotics, hormone etc.
Nutrition and health care industry:
Vacuum freeze-dried nurture products such as Royal jelly, ginseng, terrapin, rainworm, etc ,keep the final products are more natural original.
Biomedicine research:
Vacuum freeze-drying can long-termly store blood, bacteria, artery, bones, skin, cornea, nerve tissue and organs etc which can regain water and rebirth completely.
Food industry:
Drying vegetables, meat, fish, fruit, condiment instant food and specialty, etc. keeping the food's original fresh look, smell, taste, shape. The freeze-dried products can regain water completely and can be easily longer stored and less-costly transported.
Others:
Producing adiabatic ceramic in space industry; storing of specimens and relic in archaeological industry




3. Features of Our Freeze Dryer:
All the parts of the vacuum freeze dryer contacting with the products are made of SUS304 or SUS316L stainless steel;
The surface roughness of the automated lyophilizer reaches Ra≤0.5um;
The inner Chamber of the pharmaceutical freeze dryer has a smooth transition without dead corner, no objects accumulated consider for user, the structure is easy to clean;
Option for steam sterilization or chemical sterilization for the biological freeze dryer;
Except for the above, it can also provide automatic running CIP and SIP to ensure high quality of cleaning and the sterilization of both laboratory freeze dryer and industrial production freeze dryer.
 



4. Parameters of Our Freeze Dryer:



5. Company profile
Changzhou Welldone Machinery Technology Co., Ltd is a technical researching & Package solution integrating company based on two real factories (one dryer factory and one granulator factory) which has over 20 years manufacturing experiences. We are now also associating with other factory such as extractor factory, crystallization tank factory, evaporator factory, package machine factory etc to become a business league. We are able to provide more than just a single equipment, but becoming a package solution provider. Our products are widely used in pharmaceutical industry, food industry, chemical industry, environmental protection industry and so on.

Welldone actively participates in international competition, products has been exported to USA, Canada, Russia, Australia, Italy, France, Spain, Japan, Korea, Indonesia, India, Sri Lanka, Malaysia, Viet Nam, Bangladesh, Phillippines, Pakistan, Thailand, Columbia, Ecuador, Mexico, Brazil, Tajikistan, Turkey, Ukraine, Tunisia, Egypt, Algeria, South Africa, Nigeria and so on. We have won the praise of our customers with good quality and high quality service, and established a long-term win-win relationship with our customers

Welldone focuses on technology, institution and cultural precipitation. In new historical time, Welldone will continuously unfold far seeing plan, unceasingly deepen strategic idea and strongly propel production management. Based on the development of enterprises, the growth of multi-security growing way and the wisdom of the workers, Welldone will rapidly upgrade comprehensive competitive power and struggle unremittingly to create itself an innovative and cultural enterprise.